Preclinical PET-MRI Platform
A platform for radiolabelling and preclinical molecular imaging at Uppsala University.
Welcome to PPP
A Platform at Uppsala University for radiolabelling and preclinical Molecular Imaging
Positron Emission Tomography (PET) and Single Photon Emission Tomography (SPECT) are emerging methodologies in the field of molecular imaging. At the platform we bridge the gap between basic research in medicinal chemistry and clinical application of molecular imaging with PET, SPECT, MRI and CT. We develop tracers for preclinical validation using state-of-the-art in vivo and in vitro methodologies. Our small animal scanners are PET-MRI, SPECT-CT and PET-SPECT-CT. We also have access to a clinical PET-CT and PET-MRI scanners in collaboration with Uppsala Accademical Hospital.
News
- Paco Cárdenas has been awarded SciLifeLab Bioinformatics Long-term Support 2020-04-01
- Paco Cárdenas nominated as a member of the ICES/NAFO Joint Working Group on Deep-water Ecology (WGDEC). 2020-01-21
- PPP installs a new module for synthesis of radiolabelled tracers 2020-01-13
- Universitetslektor Anja Sandström vid institutionen för läkemedelskemi har tilldelats 2019 års pedagogiska pris inom området medicin och farmaci 2019-05-22
- 4 Apr 2019. Professor Mats Larhed erhåller forskningsanslag Konung Gustaf V:s och Drottning Victorias Frimurarestiftelse 2019-04-04
- Torbjörn Arvidsson vald till 1:e vice ordförande för Europafarmakopékommissionen. 2018-02-12
- 2015-03-31 Olof Erikson recieves Göran Gustafsson funding for young scientists 2018-02-12
- Plattformen för preklinisk PET-MRI utvald till SciLifeLab Pilot 2018-02-12
- Swedish research council grants Anna Orlova 4 mkr 2018-02-12
- Marc Stevens receives fellowship from Wallenberg Foundation 2018-02-12
PUBLICATIONS
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Syvänen, Stina; Fang, Xiaotian T.; Faresjö, Rebecca; Rokka, Johanna; Lannfelt, Lars; Olberg, Dag E.; Eriksson, Jonas; Sehlin, Dag
Fluorine-18-Labeled Antibody Ligands for PET Imaging of Amyloid-β in Brain
2020
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Persson, Jonas; Szalisznyo, Krisztina; Antoni, Gunnar; Wall, Anders; Fällmar, David; Zora, Hatice; Bodén, Robert
Phosphodiesterase 10A levels are related to striatal function in schizophrenia: a combined positron emission tomography and functional magnetic resonance imaging study
2020
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Fang, Xiaotian T.; Hultqvist, Greta; Meier, Silvio R.; Antoni, Gunnar; Sehlin, Dag; Syvänen, Stina
High detection sensitivity with antibody-based PET radioligand for amyloid beta in brain
2019
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Heurling, Kerstin; Ashton, Nicholas J; Leuzy, Antoine; Zimmer, Eduardo R; Blennow, Kaj; Zetterberg, Henrik; Eriksson, Jonas; Lubberink, Mark; Schöll, Michael
Synaptic vesicle protein 2A as a potential biomarker in synaptopathies
2019
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Eriksson, Jonas; Roy, Tamal; Sawadjoon, Supaporn; Bachmann, Kim; Sköld, Christian; Larhed, Mats; Weis, Jan; Selvaraju, Ram; Korsgren, Olle; Eriksson, Olof
Synthesis and initial preclinical evaluation of the CRTH2 antagonist [C-11] MK-7246
2019
Preclinical Imaging
PPP is a SciLifeLab pilot facility for radiolabelling and preclinical imaging with PET, SPECT, CT and MRI.