Publication list

List of publications in date order

  • Ding, Haozhong; Xu, Tianqi; Zhang, Jie; Tolmachev, Vladimir et al.

    Affibody-Derived Drug Conjugates Targeting HER2: Effect of Drug Load on Cytotoxicity and Biodistribution

    Part of Pharmaceutics, 2021.

    Open access
  • Tano, Hanna; Oroujeni, Maryam; Vorobyeva, Anzhelika; Westerlund, Kristina et al.

    Comparative Evaluation of Novel Lu-177-Labeled PNA Probes for Affibody-Mediated PNA-Based Pretargeting

    Part of Cancers, 2021.

    Open access
  • Xu, Tianqi; Ding, Haozhong; Vorobyeva, Anzhelika; Oroujeni, Maryam et al.

    Drug Conjugates Based on a Monovalent Affibody Targeting Vector Can Efficiently Eradicate HER2 Positive Human Tumors in an Experimental Mouse Model

    Part of Cancers, 2021.

    Open access
  • Rinne, Sara S.; Abouzayed, Ayman; Gagnon, Katherine; Tolmachev, Vladimir et al.

    Ga-66-PET-imaging of GRPR-expression in prostate cancer: production and characterization of [Ga-66]Ga-NOTA-PEG(2)-RM26

    Part of Scientific Reports, 2021.

    Open access
  • Rinne, Sara S.; Orlova, Anna; Tolmachev, Vladimir

    PET and SPECT Imaging of the EGFR Family (RTK Class I) in Oncology

    Part of International Journal of Molecular Sciences, 2021.

    Open access
  • Bragina, Olga; von Witting, Emma; Garousi, Javad; Zelchan, Roman et al.

    Phase I study of 99mTc-ADAPT6, a scaffold protein-based probe for visualization of HER2 expression in breast cancer

    Part of Journal of Nuclear Medicine, p. 493-499, 2021.

  • Bragina, O. D.; Chernov, V. I.; Garbukov, E. Yu; Doroshenko, A. V. et al.

    Possibilities of radionuclide diagnostics of Her2-positive breast cancer using technetium-99m-labeled target molecules: the first experience of clinical use

    Part of Bûlleten' sibirskoj mediciny, p. 23-30, 2021.

    Open access
  • Abouzayed, Ayman; Rinne, Sara S.; Sabahnoo, Hamideh; Sörensen, Jens et al.

    Preclinical Evaluation of 99mTc-Labeled GRPR Antagonists maSSS/SES-PEG2-RM26 for Imaging of Prostate Cancer

    Part of Pharmaceutics, 2021.

    Open access
  • Oroujeni, Maryam; Rinne, Sara S.; Vorobyeva, Anzhelika; Loftenius, Annika et al.

    Preclinical Evaluation of Tc-99m-ZHER2:41071, a Second-Generation Affibody-Based HER2-Visualizing Imaging Probe with a Low Renal Uptake

    Part of International Journal of Molecular Sciences, 2021.

    Open access
  • Garousi, Javad; von Witting, Emma; Borin, Jesper; Vorobyeva, Anzhelika et al.

    Radionuclide therapy using ABD-fused ADAPT scaffold protein: Proof of Principle

    Part of Biomaterials, 2021.

    Open access
  • Tolmachev, Vladimir; Orlova, Anna; Sörensen, Jens

    The emerging role of radionuclide molecular imaging of HER2 expression in breast cancer

    Part of Seminars in Cancer Biology, p. 185-197, 2021.

  • Oroujeni, Maryam; Xu, Tianqi; Gagnon, Katherine; Rinne, Sara S. et al.

    The Use of a Non-Conventional Long-Lived Gallium Radioisotope 66Ga Improves Imaging Contrast of EGFR Expression in Malignant Tumours Using DFO-ZEGFR: 2377 Affibody Molecule

    Part of Pharmaceutics, 2021.

    Open access
  • Tolmachev, Vladimir; Orlova, Anna

    Affibody Molecules as Targeting Vectors for PET Imaging

    Part of Cancers, 2020.

    Open access
  • Rinne, Sara S.; Leitao, Charles Dahlsson; Saleh-nihad, Zahra; Mitran, Bogdan et al.

    Benefit of Later-Time-Point PET Imaging of HER3 Expression Using Optimized Radiocobalt-Labeled Affibody Molecules

    Part of International Journal of Molecular Sciences, 2020.

    Open access
  • Deyev, Sergey M.; Vorobyeva, Anzhelika; Schulga, Alexey; Abouzayed, Ayman et al.

    Effect of a radiolabel biochemical nature on tumor-targeting properties of EpCAM-binding engineered scaffold protein DARPin Ec1

    Part of International Journal of Biological Macromolecules, p. 216-225, 2020.

    Open access
  • Leitao, Charles Dahlsson; Rinne, Sara S.; Altai, Mohamed; Vorontsova, Olga et al.

    Evaluating the Therapeutic Efficacy of Mono- and Bivalent Affibody-Based Fusion Proteins Targeting HER3 in a Pancreatic Cancer Xenograft Model.

    Part of Pharmaceutics, 2020.

    Open access
  • Myrhammar, Anders; Vorobyeva, Anzhelika; Westerlund, Kristina; Yoneoka, Shuichiro et al.

    Evaluation of an antibody-PNA conjugate as a clearing agent for antibody-based PNA-mediated radionuclide pretargeting

    Part of Scientific Reports, 2020.

    Open access
  • Vorobyeva, Anzhelika; Konovalova, Elena; Xu, Tianqi; Schulga, Alexey et al.

    Feasibility of Imaging EpCAM Expression in Ovarian Cancer Using Radiolabeled DARPin Ec1

    Part of International Journal of Molecular Sciences, 2020.

    Open access
  • Ding, Haozhong; Altai, Mohamed; Yin, Wen; Lindbo, Sarah et al.

    HER2-Specific Pseudomonas Exotoxin A PE25 Based Fusions: Influence of Targeting Domain on Target Binding, Toxicity, and In Vivo Biodistribution

    Part of Pharmaceutics, 2020.

    Open access
  • Lundmark, Fanny; Abouzayed, Ayman; Mitran, Bogdan; Rinne, Sara S. et al.

    Heterodimeric Radiotracer Targeting PSMA and GRPR for Imaging of Prostate Cancer-Optimization of the Affinity towards PSMA by Linker Modification in Murine Model

    Part of Pharmaceutics, 2020.

    Open access
  • Güler, Rezan; Svedmark, Siri Flemming; Abouzayed, Ayman; Orlova, Anna et al.

    Increasing thermal stability and improving biodistribution of VEGFR2-binding affibody molecules by a combination of in silico and directed evolution approaches

    Part of Scientific Reports, 2020.

    Open access
  • Rinne, Sara S.; Xu, Tianqi; Leitao, Charles Dahlsson; Stahl, Stefan et al.

    Influence of Residualizing Properties of the Radiolabel on Radionuclide Molecular Imaging of HER3 Using Affibody Molecules

    Part of International Journal of Molecular Sciences, 2020.

    Open access
  • Baun, Christina; Mitran, Bogdan; Rinne, Sara S.; Dam, Johan H. et al.

    Preclinical Evaluation of the Copper-64 Labeled GRPR-Antagonist RM26 in Comparison with the Cobalt-55 Labeled Counterpart for PET-Imaging of Prostate Cancer

    Part of Molecules, 2020.

    Open access
  • Abouzayed, Ayman; Tano, Hanna; Nagy, Abel; Rinne, Sara S. et al.

    Preclinical Evaluation of the GRPR-Targeting Antagonist RM26 Conjugated to the Albumin-Binding Domain for GRPR-Targeting Therapy of Cancer

    Part of Pharmaceutics, 2020.

    Open access
  • Mitran, Bogdan; Tolmachev, Vladimir; Orlova, Anna

    Radiolabeled GRPR Antagonists for Imaging of Disseminated Prostate Cancer: Influence of Labeling Chemistry on Targeting Properties

    Part of Current Medicinal Chemistry, p. 7090-7111, 2020.

  • Vorobyeva, Anzhelika; Bezverkhniaia, Ekaterina; Konovalova, Elena; Schulga, Alexey et al.

    Radionuclide Molecular Imaging of EpCAM Expression in Triple-Negative Breast Cancer Using the Scaffold Protein DARPin Ec1

    Part of Molecules, 2020.

    Open access
  • Mitran, Bogdan; Andersson, Ken Gosta; Lindström, Elin; Garousi, Javad et al.

    Affibody-mediated imaging of EGFR expression in prostate cancer using radiocobalt-labeled DOTA-Z(EGFR:2377)

    Part of Oncology Reports, p. 534-542, 2019.

  • Mitran, Bogdan; Varasteh, Zohreh; Abouzayed, Ayman; Rinne, Sara S. et al.

    Bispecific GRPR-antagonistic anti-PSMA/GRPR heterodimer for PET and SPECT diagnostic imaging of prostate cancer

    Part of Cancers, 2019.

    Open access
  • Garousi, Javad; Huizing, Fokko J.; Vorobyeva, Anzhelika; Mitran, Bogdan et al.

    Comparative evaluation of affibody- and antibody fragments-based CAIX imaging probes in mice bearing renal cell carcinoma xenografts

    Part of Scientific Reports, 2019.

    Open access
  • Garousi, Javad; Lindbo, Sarah; Borin, Jesper; von Witting, Emma et al.

    Comparative evaluation of dimeric and monomeric forms of ADAPT scaffold protein for targeting of HER2-expressing tumours

    Part of European journal of pharmaceutics and biopharmaceutics, p. 37-48, 2019.

    Open access
  • Deyev, Sergey; Vorobyeva, Anzhelika; Schulga, Alexey; Proshkina, Galina et al.

    Comparative Evaluation of Two DARPin Variants: Effect of Affinity, Size, and Label on Tumor Targeting Properties

    Part of Molecular Pharmaceutics, p. 995-1008, 2019.

  • Vorobyeva, Anzhelika; Schulga, Alexey; Konovalova, Elena; Güler, Rezan et al.

    Comparison of tumor-targeting properties of directly and indirectly radioiodinated designed ankyrin repeat protein (DARPin) G3 variants for molecular imaging of HER2

    Part of International Journal of Oncology, p. 1209-1220, 2019.

    Open access
  • Oroujeni, Maryam; Abouzayed, Ayman; Lundmark, Fanny; Mitran, Bogdan et al.

    Evaluation of Tumor-Targeting Properties of an Antagonistic Bombesin Analogue RM26 Conjugated with a Non-Residualizing Radioiodine Label Comparison with a Radiometal-Labelled Counterpart

    Part of Pharmaceutics, 2019.

    Open access
  • Rosestedt, Maria; Andersson, Ken G.; Rinne, Sara S.; Leitao, Charles Dahlsson et al.

    Improved contrast of affibody-mediated imaging of HER3 expression in mouse xenograft model through co-injection of a trivalent affibody for in vivo blocking of hepatic uptake

    Part of Scientific Reports, 2019.

    Open access
  • Ding, Haozhong; Altai, Mohamed; Rinne, Sara S.; Vorobyeva, Anzhelika et al.

    Incorporation of a Hydrophilic Spacer Reduces Hepatic Uptake of HER2-Targeting Affibody-DM1 Drug Conjugates

    Part of Cancers, 2019.

    Open access
  • Rinne, Sara S.; Leitao, Charles Dahlsson; Gentry, Joshua; Mitran, Bogdan et al.

    Increase in negative charge of 68Ga/chelator complex reduces unspecific hepatic uptake but does not improve imaging properties of HER3-targeting affibody molecules

    Part of Scientific Reports, 2019.

    Open access
  • Vorobyeva, Anzhelika; Schulga, Alexey; Rinne, Sara S.; Günther, Tyran et al.

    Indirect Radioiodination of DARPin G3 Using N-succinimidyl-Para-Iodobenzoate Improves the Contrast of HER2 Molecular Imaging

    Part of International Journal of Molecular Sciences, 2019.

    Open access
  • Dahlsson Leitao, Charles; Rinne, Sara S.; Mitran, Bogdan; Vorobyeva, Anzhelika et al.

    Molecular Design of HER3-Targeting Affibody Molecules: Influence of Chelator and Presence of HEHEHE-Tag on Biodistribution of 68Ga-Labeled Tracers

    Part of International Journal of Molecular Sciences, 2019.

    Open access
  • Vorobyeva, Anzhelika; Schulga, Alexey; Konovalova, Elena; Guler, Rezan et al.

    Optimal composition and position of histidine-containing tags improves biodistribution of Tc-99m-labeled DARP in G3

    Part of Scientific Reports, 2019.

    Open access
  • Rinne, Sara S.; Leitao, Charles Dahlsson; Mitran, Bogdan; Bass, Tarek Z. et al.

    Optimization of HER3 expression imaging using affibody molecules: Influence of chelator for labeling with indium-111

    Part of Scientific Reports, 2019.

    Open access
  • Liu, Hao; Lindbo, Sarah; Ding, Haozhong; Altai, Mohamed et al.

    Potent and specific fusion toxins consisting of a HER2-binding, ABD-derived affinity protein, fused to truncated versions of Pseudomonas exotoxin A

    Part of International Journal of Oncology, p. 309-319, 2019.

  • Mitran, Bogdan; Thisgaard, Helge; Rinne, Sara S.; Dam, Johan Hygum et al.

    Selection of an optimal macrocyclic chelator improves the imaging of prostate cancer using cobalt-labeled GRPR antagonist RM26

    Part of Scientific Reports, 2019.

    Open access
  • von Witting, Emma; Garousi, Javad; Lindbo, Sarah; Vorobyeva, Anzhelika et al.

    Selection of the optimal macrocyclic chelators for labeling with 111In and 68Ga improves contrast of HER2 imaging using engineered scaffold protein ADAPT6

    Part of European journal of pharmaceutics and biopharmaceutics, p. 109-120, 2019.

    Open access
  • Westerlund, Kristina; Vorobyeva, Anzhelika; Mitran, Bogdan; Orlova, Anna et al.

    Site-specific conjugation of recognition tags to trastuzumab for peptide nucleic acid-mediated radionuclide HER2 pretargeting

    Part of Biomaterials, p. 73-85, 2019.

    Open access
  • Abouzayed, Ayman; Yim, Cheng-Bin; Mitran, Bogdan; Rinne, Sara S. et al.

    Synthesis and Preclinical Evaluation of Radio-Iodinated GRPR/PSMA Bispecific Heterodimers for the Theranostics Application in Prostate Cancer

    Part of Pharmaceutics, 2019.

    Open access
  • Mitran, Bogdan; Rinne, Sara S.; Konijnenberg, Mark W.; Maina, Theodosia et al.

    Trastuzumab cotreatment improves survival of mice with PC-3 prostate cancer xenografts treated with the GRPR antagonist 177Lu-DOTAGA-PEG2-RM26

    Part of International Journal of Cancer, p. 3347-3358, 2019.

    Open access
  • Altai, Mohamed; Liu, Hao; Ding, Haozhong; Mitran, Bogdan et al.

    Affibody-derived drug conjugates: Potent cytotoxic molecules for treatment of HER2 over-expressing tumors

    Part of Journal of Controlled Release, p. 84-95, 2018.

  • Oroujeni, Maryam; Garousi, Javad; Andersson, K.; Löfblom, J. et al.

    Comparative evaluation of anti-EFGR affibody molecules labelled with gallium-68 and zirconium-89 using desferrioxamine B as a chelator

    Part of European Journal of Nuclear Medicine and Molecular Imaging, p. S674-S675, 2018.

  • Vorobyeva, Anzhelika; Bragina, Olga; Altai, Mohamed; Mitran, Bogdan et al.

    Comparative Evaluation of Radioiodine and Technetium-Labeled DARPin 9_29 for Radionuclide Molecular Imaging of HER2 Expression in Malignant Tumors

    Part of Contrast Media & Molecular Imaging, 2018.

    Open access
  • Summer, Dominik; Garousi, Javad; Oroujeni, Maryam; Mitran, Bogdan et al.

    Cyclic versus Noncyclic Chelating Scaffold for Zr-89-Labeled ZEGFR:2377 Affibody Bioconjugates Targeting Epidermal Growth Factor Receptor Overexpression

    Part of Molecular Pharmaceutics, p. 175-185, 2018.

    Open access