Publikationer

  • Tomberg, Anna; Muratore, Michael Eric; Johansson, Magnus Jan; Terstiege, Ina et al.

    Relative Strength of Common Directing Groups in Palladium-Catalyzed Aromatic C-H Activation

    Ingår i ISCIENCE, s. 373 373-+ +, 2019.

    Open access
  • Rodrigues, Leticia; Schneider, Fabian; Zhang, Xiaohan; Larsson, Elin et al.

    Cellular uptake of self-assembled phytantriol-based hexosomes is independent of major endocytic machineries

    Ingår i Journal of Colloid and Interface Science, s. 820-833, 2019.

  • Söderström, Marcus; Zamaratski, Edouard; Odell, Luke R.

    Thiomethylation, Nitro Reduction and Tandem Reduction/SMe Insertion of Nitrogen Heterocycles Using BF3⦁SMe2

    Ingår i European Journal of Organic Chemistry, s. 5402-5408, 2019.

    Open access
  • Eriksson, Jonas; Roy, Tamal; Sawadjoon, Supaporn; Bachmann, Kim et al.

    Synthesis and preclinical evaluation of the CRTH2 antagonist [11C]MK-7246 as a novel PET tracer and potential surrogate marker for pancreatic beta-cell mass

    Ingår i Nuclear Medicine and Biology, s. 1-10, 2019.

    Open access
  • Chinthakindi, Praveen K.; Benediktsdottir, Andrea; Ibrahim, Ayah; Wared, Atta et al.

    Synthesis of Sulfonimidamide-Based Amino Acid Building Blocks with Orthogonal Protecting Groups

    Ingår i European Journal of Organic Chemistry, s. 1045-1057, 2019.

  • Hallberg, Mathias; Sandström, Anja

    From the Anti-Nociceptive Substance P Metabolite Substance P (1-7) to Small Peptidomimetics

    Ingår i Current protein and peptide science, s. 1038-1048, 2018.

  • Chinthakindi, Praveen K.; Arvidsson, Per I.

    Sulfonyl Fluorides (SFs): More Than Click Reagents?

    Ingår i European Journal of Organic Chemistry, s. 3648-3666, 2018.

  • Szałaj, Natalia; Lu, Lu; Benediktsdottir, Andrea; Zamaratski, Edouard et al.

    Boronic ester-linked macrocyclic lipopeptides as serine protease inhibitors targeting Escherichia coli type I signal peptidase.

    Ingår i European Journal of Medicinal Chemistry, s. 1346-1360, 2018.

  • Skogh, Anna; Lesniak, Anna; Sköld, Christian; Karlgren, Maria et al.

    An imidazole based H-Phe-Phe-NH2 peptidomimetic with anti-allodynic effect in spared nerve injury mice

    Ingår i Bioorganic & Medicinal Chemistry Letters, s. 2446-2450, 2018.

  • Belfrage, Anna Karin; Abdurakhmanov, Eldar; Åkerblom, Eva; Brandt, Peter et al.

    Pan-NS3 protease inhibitors of hepatitis C virus based on an R3-elongated pyrazinone scaffold

    Ingår i European Journal of Medicinal Chemistry, s. 453-464, 2018.

  • Skogh, Anna; Lesniak, Anna; Gaugaz, Fabienne Z.; Svensson, Richard et al.

    Impact of N-methylation of the substance P 1-7 amide on anti-allodynic effect in mice after peripheral administration

    Ingår i European Journal of Pharmaceutical Sciences, s. 533-540, 2017.

  • Skogh, Anna; Lesniak, Anna; Gaugaz, Fabienne Z.; Svensson, Richard et al.

    Importance of N-and C-terminal residues of substance P 1-7 for alleviating allodynia in mice after peripheral administration

    Ingår i European Journal of Pharmaceutical Sciences, s. 345-351, 2017.

  • Skogh, Anna; Friis, Stig D.; Skrydstrup, Troels; Johansson, Anja

    Palladium-Catalyzed Aminocarbonylation in Solid-Phase Peptide Synthesis: A Method for Capping, Cyclization, and Isotope Labeling

    Ingår i Organic Letters, s. 2873-2876, 2017.

  • Lindh, Martin; Karlén, Anders; Norinder, Ulf

    Predicting the Rate of Skin Penetration Using an Aggregated Conformal Prediction Framework

    Ingår i Molecular Pharmaceutics, s. 1571-1576, 2017.

  • Alogheli, Hiba; Olanders, Gustav; Schaal, Wesley; Brandt, Peter et al.

    Docking of Macrocycles: Comparing Rigid and Flexible Docking in Glide

    Ingår i Journal of Chemical Information and Modeling, s. 190-202, 2017.

  • De Rosa, Maria; Lu, Lu; Zamaratski, Edouard; Szałaj, Natalia et al.

    Design, synthesis and in vitro biological evaluation of oligopeptides targeting E. coli type I signal peptidase (LepB)

    Ingår i Bioorganic & Medicinal Chemistry, s. 897-911, 2017.

    Open access
  • Sawant, Rajiv T.; Stevens, Marc Y.; Sköld, Christian; Odell, Luke R.

    Microwave-Assisted Branching Cascades: A Route to Diverse 3,4-Dihydroquinazolinone-Embedded Polyheterocyclic Scaffolds

    Ingår i Organic Letters, s. 5392-5395, 2016.

  • Kostyanev, T.; Bonten, M. J. M.; O'Brien, S.; Steel, H. et al.

    The Innovative Medicines Initiative's New Drugs for Bad Bugs programme: European public-private partnerships for the development of new strategies to tackle antibiotic resistance

    Ingår i Journal of Antimicrobial Chemotherapy, s. 290-295, 2016.

  • Sallander, Jessica; Wallinder, Charlotta; Hallberg, Anders; Åqvist, Johan et al.

    Structural determinants of subtype selectivity and functional activity of angiotensin II receptors

    Ingår i Bioorganic & Medicinal Chemistry Letters, s. 1355-1359, 2016.

  • Belfrage, Anna Karin; Abdurakhmanov, Eldar; Åkerblom, Eva; Brandt, Peter et al.

    Discovery of pyrazinone based compounds that potently inhibit the drug resistant enzyme variant R155K of the hepatitis C virus NS3 protease

    Ingår i Bioorganic & Medicinal Chemistry, s. 2603-2620, 2016.

  • Belfrage, Anna Karin; Wakchaure, Prasad; Larhed, Mats; Sandström, Anja

    Palladium-Catalyzed Carbonylation of Aryl Iodides with Sulfinamides

    Ingår i European Journal of Organic Chemistry, s. 7069-7074, 2015.

  • Svensson, Fredrik; Engen, Karin; Lundbäck, Thomas; Larhed, Mats et al.

    Virtual Screening for Transition State Analogue Inhibitors of IRAP Based on Quantum Mechanically Derived Reaction Coordinates

    Ingår i Journal of Chemical Information and Modeling, s. 1984-1993, 2015.

  • Russo, Francesco; Gising, Johan; Åkerbladh, Linda; Roos, Annette K. et al.

    Optimization and Evaluation of 5-Styryl-Oxathiazol-2-one Mycobacterium tuberculosis Proteasome Inhibitors as Potential Antitubercular Agents

    Ingår i ChemistryOpen, s. 342-362, 2015.

    Open access
  • Borhade, Sanjay R.; Svensson, Richard; Brandt, Peter; Artursson, Per et al.

    Preclinical Characterization of Acyl Sulfonimidamides: Potential Carboxylic Acid Bioisosteres with Tunable Properties

    Ingår i ChemMedChem, s. 455-460, 2015.

  • Lindh, Martin; Svensson, Fredrik; Schaal, Wesley; Zhang, Jin et al.

    Toward a Benchmarking Data Set Able to Evaluate Ligand- and Structure-based Virtual Screening Using Public HTS Data

    Ingår i Journal of Chemical Information and Modeling, s. 343-353, 2015.

  • Jonsson, Anna; Fransson, Rebecca; Haramaki, Yutaka; Skogh, Anna et al.

    Small constrained SP1-7 analogues bind to a unique site and promote anti-allodynic effects following systemic injection in mice

    Ingår i Neuroscience, s. 112-119, 2015.

  • Belfrage, Anna Karin; Gising, Johan; Svensson, Fredrik; Åkerblom, Eva et al.

    Efficient and Selective Palladium-Catalysed C-3 Urea Couplings to 3,5-Dichloro-2(1H)-pyrazinones

    Ingår i European Journal of Organic Chemistry, s. 978-986, 2015.

    Open access
  • Wakchaure, Prasad; Borhade, Sanjay; Sandström, Anja; Arvidsson, Per

    Synthesis of Vinyl- and Aryl–Acyl Sulfonimidamides Through Pd-Catalyzed Carbonylation Using Mo(CO)6 as ex situ CO Source

    Ingår i European Journal of Organic Chemistry, s. 213-219, 2015.

  • Karlsson, Christoffer; Blom, Magnus; Johansson, Miranda; Jansson, Anna M. et al.

    Phototriggerable peptidomimetics for the inhibition of Mycobacterium turberculosis ribonucleotide reductase by targeting protein-protein binding

    Ingår i Organic and biomolecular chemistry, s. 2612-2621, 2015.

  • Wallinder, Charlotta; Sköld, Christian; Botros, Milad; Guimond, Marie-Odile et al.

    Interconversion of Functional Activity by Minor Structural Alterations in Nonpeptide AT2 Receptor Ligands

    Ingår i ACS Medicinal Chemistry Letters, s. 178-182, 2015.

  • Skillinghaug, Bobo; Sköld, Christian; Behrends, Malte; Sävmarker, Jonas et al.

    Palladium(II) catalyzed desulfitative coupling reactions of sodium aryl sulfinates and nitriles: Scope, limitations, and mechanistic studies

    Ingår i Abstract of Papers of the American Chemical Society, 2014.

  • Borhade, Sanjay R; Rosenström, Ulrika; Sävmarker, Jonas; Lundbäck, Thomas et al.

    Inhibition of Insulin-Regulated Aminopeptidase (IRAP) by Arylsulfonamides

    Ingår i ChemistryOpen, s. 256-263, 2014.

  • Skillinghaug, Bobo; Sköld, Christian; Rydfjord, Jonas; Svensson, Fredrik et al.

    Palladium(II)-Catalyzed Desulfitative Synthesis of Aryl Ketones from Sodium Arylsulfinates and Nitriles: Scope, Limitations, and Mechanistic Studies

    Ingår i Journal of Organic Chemistry, s. 12018-12032, 2014.

  • Fransson, Rebecca; Nordvall, Gunnar; Bylund, Johan; Carlsson-Jonsson, Anna et al.

    Exploration and pharmacokinetic profiling of phenylalanine based carbamates as novel substance p 1-7 analogues

    Ingår i ACS Medicinal Chemistry Letters, s. 1272-1277, 2014.

  • Lampa, Anna; Alogheli, Hiba; Ehrenberg, Angelica E.; Åkerblom, Eva et al.

    Vinylated linear P2 pyrimidinyloxyphenylglycine based inhibitors of the HCV NS3/4A protease and corresponding macrocycles

    Ingår i Bioorganic & Medicinal Chemistry, s. 6595-6615, 2014.

  • Guimond, Marie-Odile; Hallberg, Mathias; Gallo-Payet, Nicole; Wallinder, Charlotta

    Saralasin and Sarile Are AT2 Receptor Agonists

    Ingår i ACS Medicinal Chemistry Letters, s. 1129-1132, 2014.

  • Carlsson-Jonsson, Anna; Gao, Tianle; Hao, Jing-Xia; Fransson, Rebecca et al.

    N-terminal truncations of substance P1-7 amide affect its action on spinal cord injury-induced mechanical allodynia in rats

    Ingår i European Journal of Pharmacology, s. 319-325, 2014.

  • Hughes, Diarmaid; Karlén, Anders

    Discovery and preclinical development of new antibiotics

    Ingår i Upsala Journal of Medical Sciences, s. 162-169, 2014.

  • Behrends, Malte; Wallinder, Charlotta; Wieckowska, Anna; Guimond, Marie-Odile et al.

    N-Aryl Isoleucine Derivatives as Angiotensin II AT(2) Receptor Ligands

    Ingår i ChemistryOpen, s. 65-75, 2014.

    Open access
  • Lampa, Anna; Bergman, Sara; Svahn Gustafsson, Sofia; Alogheli, Hiba et al.

    Novel Peptidomimetic Hepatitis C Virus NS3/4A Protease Inhibitors Spanning the P2–P1′ Region

    Ingår i ACS Medicinal Chemistry Letters, s. 249-254, 2014.

  • Veron, Jean-Baptiste; Joshi, Advait; Wallinder, Charlotta; Larhed, Mats et al.

    Synthesis and evaluation of isoleucine derived angiotensin II AT(2) receptor ligands

    Ingår i Bioorganic & Medicinal Chemistry Letters, s. 476-479, 2014.

  • Gising, Johan; Belfrage, Anna Karin; Alogheli, Hiba; Ehrenberg, Angelica et al.

    Achiral Pyrazinone-Based Inhibitors of the Hepatitis C Virus NS3 Protease and Drug-Resistant Variants with Elongated Substituents Directed Toward the S2 Pocket

    Ingår i Journal of Medicinal Chemistry, s. 1790-1801, 2014.

  • Skogh, Anna; Fransson, Rebecca; Sköld, Christian; Larhed, Mats et al.

    Aminocarbonylation of 4-Iodo-1H-imidazoles with an Amino Acid Amide Nucleophile: Synthesis of Constrained H-Phe-Phe-NH2 Analogues

    Ingår i Journal of Organic Chemistry, s. 12251-12256, 2013.

  • Rydfjord, Jonas; Svensson, Fredrik; Trejos, Alejandro; Sjöberg, Per J. R. et al.

    Decarboxylative Palladium(II)-Catalyzed Synthesis of Aryl Amidines from Aryl Carboxylic Acids: Development and Mechanistic Investigation

    Ingår i Chemistry - A European Journal, s. 13803-13810, 2013.

    Open access
  • Wannberg, Johan; Wallinder, Charlotta; Unlusoy, Meltem; Sköld, Christian et al.

    One-Pot, Two-Step, Microwave-Assisted Palladium-Catalyzed Conversion of Aryl Alcohols to Aryl Fluorides via Aryl Nonaflates

    Ingår i Journal of Organic Chemistry, s. 4184-4189, 2013.

  • Borhade, Sanjay R.; Sandström, Anja; Arvidsson, Per I.

    Synthesis of Novel Aryl and Heteroaryl Acyl Sulfonimidamides via Pd-Catalyzed Carbonylation Using a Nongaseous Precursor

    Ingår i Organic Letters, s. 1056-1059, 2013.

  • Jansson, Anna; Więckowska, Anna; Björkelid, Christofer; Yahiaoui, Samir et al.

    DXR Inhibition by Potent Mono- and Disubstituted Fosmidomycin Analogues

    Ingår i Journal of Medicinal Chemistry, s. 6190-6199, 2013.

    Open access
  • Svensson, Fredrik; Mane, Rajendra S.; Sävmarker, Jonas; Larhed, Mats et al.

    Theoretical and Experimental Investigation of Palladium(II)-Catalyzed Decarboxylative Addition of Arenecarboxylic Acid to Nitrile

    Ingår i Organometallics, s. 490-497, 2013.

  • Shum, Michael; Pinard, Sandra; Guimond, Marie-Odile; Labbe, Sebastien M. et al.

    Angiotensin II type 2 receptor promotes adipocyte differentiation and restores adipocyte size in high-fat/high-fructose diet-induced insulin resistance in rats

    Ingår i American Journal of Physiology. Endocrinology and Metabolism, s. E197-E210, 2013.

  • Fransson, Rebecca; Sköld, Christian; Kratz, Jadel M; Svensson, Richard et al.

    Constrained H-Phe-Phe-NH2 Analogues With High Affinity to the Substance P 1-7 Binding Site and With Improved Metabolic Stability and Cell Permeability

    Ingår i Journal of Medicinal Chemistry, s. 4953-4965, 2013.

  • Nurbo, Johanna; Ericsson, Daniel J.; Rosenström, Ulrika; Muthas, Daniel et al.

    Novel pseudopeptides incorporating a benzodiazepine-based turn mimetic – targeting Mycobacterium tuberculosis ribonucleotide reductase

    Ingår i Bioorganic & Medicinal Chemistry, s. 1992-2000, 2013.

  • Gallo-Payet, Nicole; Shum, Michael; Baillargeon, Jean-Patrice; Langlois, Marie-France et al.

    AT2 Receptor Agonists: Exploiting the Beneficial Arm of Ang II Signaling

    Ingår i current hypertension reviews, s. 47-59, 2012.

  • Guimond, Marie-Odile; Wallinder, Charlotta; Altermann, Mathias; Hallberg, Anders et al.

    Comparative functional properties of two structurally similar selective nonpeptide drug-like ligands for the angiotensin II type-2 (AT2) receptor. Effects on neurite outgrowth in NG108-15 cells

    Ingår i European Journal of Pharmacology - Molecular Pharmacology Section, s. 160-171, 2012.

  • Fransson, Rebecca; Sandström, Anja

    Use of Peptides as Drug Leads: A Case Story on the Development of Dipeptides Corresponding to the Heptapeptide Substance P(1-7), with Intriguing Effects on Neuropathic Pain

    Ingår i In Neuropeptides in Neuroprotection and Neuroregeneration., s. 253-270, 2012.

  • Claerhout, Stijn; Sharma, Sweta; Sköld, Christian; Cavaluzzo, Claudia et al.

    Synthesis of functionalized furopyrazines as restricted dipeptidomimetics

    Ingår i Tetrahedron, s. 3019-3029, 2012.

  • Sköld, Christian; Kleimark, Jonatan; Trejos, Alejandro; Odell, Luke R. et al.

    Transmetallation Versus β-Hydride Elimination: The Role of 1,4 Benzoquinone in Chelation-Controlled Arylation Reactions with Arylboronic Acids

    Ingår i Chemistry - A European Journal, s. 4714-4722, 2012.

    Open access
  • Gising, Johan; Nilsson, Mikael T; Odell, Luke R; Yahiaoui, Samir et al.

    Trisubstituted Imidazoles as Mycobacterium tuberculosis Glutamine Synthetase Inhibitors

    Ingår i Journal of Medicinal Chemistry, s. 2894-2898, 2012.

    Open access
  • Andappan, Murugaiah M. S.; Wu, Xiongyu; Wallinder, Charlotta; Mahalingam, A. K. et al.

    From the First Selective Non-Peptide AT(2) Receptor Agonist to Structurally Related Antagonists

    Ingår i Journal of Medicinal Chemistry, s. 2265-2278, 2012.

  • Svensson, Fredrik; Karlén, Anders; Sköld, Christian

    Virtual Screening Data Fusion Using Both Structure- and Ligand-Based Methods

    Ingår i Journal of Chemical Information and Modeling, s. 225-232, 2012.

  • Nordqvist, Anneli; Nilsson, Mikael T.; Lagerlund, Olof; Muthas, Daniel et al.

    Synthesis, biological evaluation and X-ray crystallographic studies of imidazo[1,2-a]-pyridine based Mycobacterium tuberculosis glutamine synthetase inhibitors

    Ingår i MedChemComm, s. 620-626, 2012.

  • Gallo-Payet, Nicole; Guimond, Marie-Odile; Bilodeau, Lyne; Wallinder, Charlotta et al.

    Angiotensin II, a neuropeptide at frontier between endocrinology and neuroscience:  is there a link between the angiotensin II type 2 receptor andAlzheimer’s disease?

    Ingår i Frontiers in Endocrinology, s. Article 17-, 2011.

  • Ohsawa, Masahiro; Carlsson, Anna; Asato, Megumi; Koizumi, Takayuki et al.

    The dipeptide Phe-Phe amide attenuates signs of hyperalgesia, allodynia and nociception in diabetic mice using a mechanism involving the sigma receptor system

    Ingår i Molecular Pain, s. 85-, 2011.

    Open access
  • Andaloussi, Mounir; Lindh, Martin; Björkelid, Christofer; Suresh, Surisetti et al.

    Substitution of the phosphonic acid and hydroxamic acid functionalities of the DXR inhibitor FR900098: An attempt to improve the activity against Mycobacterium tuberculosis

    Ingår i Bioorganic & Medicinal Chemistry Letters, s. 5403-5407, 2011.

  • Nordqvist, Anneli; Björkelid, Christofer; Andaloussi, Mounir; Jansson, Anna M. et al.

    Synthesis of Functionalized Cinnamaldehyde Derivatives by an Oxidative Heck Reaction and Their Use as Starting Materials for Preparation of Mycobacterium tuberculosis 1-Deoxy-D-xylulose-5-phosphate Reductoisomerase Inhibitors

    Ingår i Journal of Organic Chemistry, s. 8986-8998, 2011.

    Open access
  • Lampa, Anna; Ehrenberg, Angelica E.; Vema, Aparna; Åkerblom, Eva et al.

    P2-P1 ' macrocyclization of P2 phenylglycine based HCV NS3 protease inhibitors using ring-closing metathesis

    Ingår i Bioorganic & Medicinal Chemistry, s. 4917-4927, 2011.

  • Andaloussi, Mounir; Henriksson, Lena M.; Wieckowska, Anna; Lindh, Martin et al.

    Design, Synthesis, and X-ray Crystallographic Studies of alpha-Aryl Substituted Fosmidomycin Analogues as Inhibitors of Mycobacterium tuberculosis 1-Deoxy-D-xylulose 5-Phosphate Reductoisomerase

    Ingår i Journal of Medicinal Chemistry, s. 4964-4976, 2011.

    Open access
  • Steckelings, U. Muscha; Larhed, Mats; Hallberg, Anders; Widdop, Robert E. et al.

    Non-peptide AT2-receptor agonists

    Ingår i Current opinion in pharmacology (Print), s. 187-192, 2011.

  • Ohsawa, Masahiro; Carlsson, Anna; Asato, Megumi; Koizumi, Takayuki et al.

    The effect of substance P1-7 amide on nociceptive threshold in diabetic mice

    Ingår i Peptides, s. 93-98, 2011.

  • Andersson, Hanna; Demaegdt, Heidi; Johnsson, Anders; Vauquelin, Georges et al.

    Potent Macrocyclic Inhibitors of Insulin-Regulated Aminopeptidase (IRAP) by Olefin Ring-Closing Metathesis

    Ingår i Journal of Medicinal Chemistry, s. 3779-3792, 2011.

  • Gising, Johan; Belfrage, Anna Karin; Örtqvist, Pernilla; Larhed, Mats et al.

    Hepatitis C protease inhibitors based on 2(1H)-pyrazinones

    Ingår i Abstract of Papers of the American Chemical Society, s. 116-MEDI-, 2010.

  • Fransson, Rebecca; Botros, Milad; Sköld, Christian; Nyberg, Fred et al.

    Discovery of Dipeptides with High Affinity to the Specific Binding Site for Substance P1-7

    Ingår i Journal of Medicinal Chemistry, s. 2383-2389, 2010.

  • Mahalingam, A. K.; Wan, Yiqian; Murugaiah, A. M. S.; Wallinder, Charlotta et al.

    Selective angiotensin II AT(2) receptor agonists with reduced CYP 450 inhibition

    Ingår i Bioorganic & Medicinal Chemistry, s. 4570-4590, 2010.

  • Ax, Anna; Joshi, Advait A.; Orrling, Kristina M.; Vrang, Lotta et al.

    Synthesis of a small library of non-symmetric cyclic sulfamide HIV-1 protease inhibitors

    Ingår i Tetrahedron, s. 4049-4056, 2010.

  • Örtqvist, Pernilla; Vema, Aparna; Ehrenberg, Angelica E; Dahl, Göran et al.

    Structure-activity relationships of HCV NS3 protease inhibitors evaluated on the drug-resistant variants A156T and D168V

    Ingår i Antiviral Therapy, s. 841-852, 2010.

  • Lampa, Anna; Ehrenberg, Angelica E.; Gustafsson, Sofia S.; Vema, Aparna et al.

    Improved P2 phenylglycine-based hepatitis C virus NS3 protease inhibitors with alkenylic prime-side substituents

    Ingår i Bioorganic & Medicinal Chemistry, s. 5413-5424, 2010.

  • Andersson, Hanna; Demaegdt, Heidi; Vauquelin, Georges; Lindeberg, Gunnar et al.

    Disulfide cyclized tripeptide analogues of angiotensin IV as potent and selective inhibitors of insulin-regulated aminopeptidase (IRAP)

    Ingår i Journal of Medicinal Chemistry, s. 8059-8071, 2010.

  • Örtqvist, Pernilla; Gising, Johan; Ehrenberg, Angelica; Vema, Aparna et al.

    Discovery of Achiral Inhibitors of the Hepatitis C Virus NS3 Protease based on 2(1H)-pyrazinones

    Ingår i Bioorganic & Medicinal Chemistry, s. 6512-6525, 2010.

  • Åberg, Ola; Stevens, Marc; Lindh, Jonas; Wallinder, Charlotta et al.

    Synthesis and evaluation of a 11C-labelled angiotensin II AT2 receptor ligand

    Ingår i Journal of labelled compounds & radiopharmaceuticals, s. 616-624, 2010.

  • Bergström, Christel A S; Bolin, Sara; Artursson, Per; Rönn, Robert et al.

    Hepatitis C virus NS3 protease inhibitors: large, flexible molecules of peptide origin show satisfactory permeability across Caco-2 cells

    Ingår i European Journal of Pharmaceutical Sciences, s. 556-563, 2009.

  • Gising, Johan; Örtqvist, Pernilla; Sandström, Anja; Larhed, Mats

    A straightforward microwave method for rapid synthesis of N-1, C-6 functionalized 3,5-dichloro-2(1H)-pyrazinones

    Ingår i Organic and biomolecular chemistry, s. 2809-2815, 2009.

  • Odell, Luke R.; Nilsson, Mikael T.; Gising, Johan; Lagerlund, Olof et al.

    Functionalized 3-amino-imidazo[1,2-a]pyridines: A novel class of drug-like Mycobacterium tuberculosis glutamine synthetase inhibitors

    Ingår i Bioorganic & Medicinal Chemistry Letters, s. 4790-4793, 2009.

  • Zhou, Qin; Carlsson, Anna; Botros, Milad; Fransson, Rebecca et al.

    The C-terminal amidated analogue of the Substance P (SP) fragment SP (1-7) attenuates the expression of naloxone- precipitated withdrawal in morphine dependent rats

    Ingår i Peptides, s. 2418-2422, 2009.

  • Nilsson, Mikael T.; Krajewski, Wojciech W.; Srinivasa, Bachally R.; Yahiaoui, Samir et al.

    Structural basis for the inhibition of Mycobacterium tuberculosis glutamine synthetase by novel ATP-competitive inhibitors

    Ingår i Journal of Molecular Biology, s. 504-513, 2009.

    Open access
  • Rönn, Robert; Sandström, Anja

    New developments in the discovery of agents to treat hepatitis C

    Ingår i Current Topics in Medicinal Chemistry, s. 533-562, 2008.

  • Andersson, Hanna; Demaegdt, Heidi; Vauquelin, Georges; Lindeberg, Gunnar et al.

    Ligands to the (IRAP)/AT4 receptor encompassing a 4-hydroxydiphenylmethane scaffold replacing Tyr2

    Ingår i Bioorganic & Medicinal Chemistry, s. 6924-6935, 2008.

  • Fransson, Rebecca; Botros, Milad; Nyberg, Fred; Lindeberg, Gunnar et al.

    Small peptides mimicking substance P (1-7) and encompassing a C-terminal amide functionality

    Ingår i Neuropeptides, s. 31-37, 2008.

  • Wallinder, Charlotta; Botros, Milad; Rosenström, Ulrika; Guimond, Marie-Odile et al.

    Selective angiotensin II AT2 receptor agonists: Benzamide structure–activity relationships

    Ingår i Bioorganic & Medicinal Chemistry, s. 6841-6849, 2008.

  • Nurbo, Johanna; Peterson, Shane D.; Dahl, Göran; Danielson, U. Helena et al.

    β-Amino acid substitutions and structure-based CoMFA modeling of hepatitis C virus NS3 protease inhibitors

    Ingår i Bioorganic & Medicinal Chemistry, s. 5590-5605, 2008.

  • Rönn, Robert; Lampa, Anna; Peterson, Shane D.; Gossas, Thomas et al.

    Hepatitis C Virus NS3 Protease Inhibitors Comprising a Novel Aromatic P1 Moiety

    Ingår i Bioorganic & Medicinal Chemistry, s. 2955-2967, 2008.

  • Dahl, Göran; Sandström, Anja; Åkerblom, Eva; Danielson, U. Helena

    Resistance profiling of hepatitis C virus protease inhibitors using full-length NS3

    Ingår i Antiviral Therapy, s. 733-740, 2007.

  • Dahl, Göran; Sandström, Anja; Åkerblom, Eva; Danielson, U. Helena

    Effects on protease inhibition by modifying of helicase residues in hepatitis C virus nonstructural protein 3

    Ingår i The FEBS Journal, s. 5979-5986, 2007.

  • Rönn, Robert; Gossas, Thomas; Sabnis, Yogesh A.; Daoud, Hanna et al.

    Evaluation of a diverse set of potential P1 carboxylic acid bioisosteres in hepatitis C virus NS3 protease inhibitors

    Ingår i Bioorganic & Medicinal Chemistry, s. 4057-4068, 2007.

  • Poliakov, Anton; Sandström, Anja; Åkerblom, Eva; Danielson, U. Helena

    Mechanistic studies of electrophilic protease inhibitors of full length hepatic C virus (HCV) NS3

    Ingår i Journal of enzyme inhibition and medicinal chemistry (Print), s. 191-199, 2007.

  • Muthas, Daniel; Lek, Per M.; Nurbo, Johanna; Karlén, Anders et al.

    Focused hierarchical design of peptide libraries - follow the lead

    Ingår i Journal of Chemometrics, s. 486-495, 2007.

  • Lagerlund, Olof; Odell, Luke R.; Mowbray, Sherry L.; Nilsson, Mikael T. et al.

    Microwave-enhanced alpha-arylation of a protected glycine in water: evaluation of 3-phenylglycine derivatives as inhibitors of the tuberculosis enzyme, glutamine synthetase

    Ingår i Combinatorial chemistry & high throughput screening, s. 783-789, 2007.

  • Sunnerheim, Kerstin; Nordqvist, Anneli; Nordlander, Göran; Borg-Karlson, Anna-Karin et al.

    Quantitative structure-activity relationships of pine weevil antifeedants, a multivariate approach

    Ingår i Journal of Agricultural and Food Chemistry, s. 9365-9372, 2007.

  • Nurbo, Johanna; Roos, Annette K; Muthas, Daniel; Wahlström, Erik et al.

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